A brief summary of current research.
The neural correlates of cognitive fatigue in traumatic brain injury using functional MRI
Kohl, AD, Wylie, GR, Genova, HM, Hillary, FG, DeLuca, J Brain Injury, Volume 23, Issue 5 May 2009, pp 420 – 432.
This study used functional magnetic resonance imaging (fMRI) to objectively assess cognitive fatigue in people with TBI. When performing a cognitive task, the participants with TBI showed increased brain activity over time, compared to the non-injured participants. This increased activity in various parts of the brain, which indicates increased cerebral "effort," might manifest as an individual’s feeling of cognitive fatigue.
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I'm 5 years out from my TBI. 'Neuro-fatigue' rules my life. I'm unable to teach and had to end my 15 year career. I've had doctors, neurologists, have no knowledge of what this is. Talk about feeling hopeless. My neuropsychologist gets this and helps me with strategies.